Foshan Sanshui Xincheng Hospital, namely the the Pearl River Hospital of Southern Medical University (Sanshui Hospital), is located in the southeast of the junction of Hongling Road and Zongjiu Road, Yundonghai Street. The project officially started construction in 2019. Currently, the main structures of the hospital's outpatient and inpatient building, living and logistics building, science and education building, and academic center have been completed and entered the stage of interior decoration and mechanical and electrical installation.

The construction project of Sanshui District New City Hospital aims to build a modern "tertiary" comprehensive hospital that integrates "medicine, education, research, and prevention", with the basic positioning and strategic goal of being a high-level regional medical center and translational medicine center based on Sanshui, serving Guangfo Zhao, and radiating to the northwest region of Guangdong.

Sanshui District Xincheng Hospital mainly has four functional areas, namely outpatient and inpatient building, living and logistics building, science and education building, and academic center. Among them, the outpatient and inpatient building has a total of 17 floors, with inpatient departments on floors 6 and above, outpatient and medical technology departments on floors 1-5, and a total of 18 operating rooms. The negative floor is the imaging center and radiology department, and will also be equipped with supermarkets and dining areas. After the completion of Xincheng Hospital, 999 beds and 2000 medical staff will be added to Sanshui District, and high-end medical technology from the Pearl River Hospital of Southern Medical University will be introduced to build a comprehensive tertiary hospital integrating medical treatment, rehabilitation, prevention and health care, teaching and research